The Journal
D-Mannose: The Science of a Simple Sugar in Canine Urinary Health
D-Mannose is a simple sugar isomer chemically related to glucose, but it functions very differently in the body. It does not behave as a fuel source.
The Science of D-Mannose
D-Mannose is a simple sugar isomer chemically related to glucose, but it functions very differently in the body. It does not behave as a fuel source. It occurs naturally in small amounts in fruit, including cranberries.
Why NutraWag Chose This Ingredient
We selected D-Mannose as a core ingredient for our urinary formula to help support urinary tract health. Urinary Care+ contains 250 mg of D-Mannose in every 1 mL, and every milligram is listed on the label.
Many supplements rely on low-dose cranberry powder alone, which often lacks a meaningful concentration of its key compounds (PACs). By utilizing D-Mannose as a primary ingredient alongside a concentrated cranberry extract, NutraWag does not rely on cranberry alone.
Always consult your veterinarian before starting a new supplement, and see your veterinarian promptly if you notice any change in your dog’s urination.
References
Scientific References
- Scribano, F., Marchetti, P., & Mura, U. (2021). Considerations on D-mannose Mechanism of Action and Consequent Classification of Marketed Healthcare Products. Frontiers in Pharmacology, 12, 636377.
Note: A review article on D-mannose and the classification of marketed healthcare products.
Disclaimer: This reference is provided for educational purposes about the ingredient and is not intended to imply specific outcomes in dogs.
Every milligram, on the label
Read it the way you read your own.
No proprietary blends. No combined “active mg” totals. Every active ingredient and its exact amount per 1 mL dropper—on the label, and on every product page.
| Ingredient | Amount |
|---|---|
| D-Mannose | 250 mg |
| Dandelion Leaf extract | 30 mg |
| Stinging Nettle extract | 30 mg |
| Cornsilk extract | 25 mg |
| Cranberry extract | 10 mg |
Non-medicinal: vegetable glycerin, reverse osmosis purified water, natural bacon flavour. VHP NN.R0G9.
| Ingredient | Amount |
|---|---|
| L-Theanine>99% pure isolate | 50 mg |
| German chamomile flower extractstandardized to 1.2% apigenin | 25 mg |
| Lemon balm leaf extractstandardized to 5% rosmarinic acid | 25 mg |
Non-medicinal: vegetable glycerin, reverse osmosis purified water, natural bacon flavour. VHP NN.W2S1.